1/10
A 67-year-old man was found dead for unknown reasons. He has a long history of hypertension and suffered a myocardial infarction 1 year ago. The family requested that an autopsy be performed. Gross examination of his heart shows scarring and enlargement of the left ventricle. A histological section of his left ventricle is shown below.

The type of collagen seen in the image is most similar to collagen found in which of the following tissues?

The type of collagen seen in the image is most similar to collagen found in which of the following tissues?
- Basementmembrane
- Granulationtissue
- Hyalinecartilage
- Nucleuspulposus
- Tendon
2/10
Endocrinologists investigating the anatomic features of adrenal hormone synthesis prepare several gross autopsy specimens for histologic analysis. A section through the center of a normal adrenal gland after staining with hematoxylin and eosin is shown in the image below.

The tissue indicated by the arrow is most likely to contain cells activated by which of the following substance?

The tissue indicated by the arrow is most likely to contain cells activated by which of the following substance?
- Acetylcholine
- ACTH
- AngiotensinII
- Epinephrine
- Norepinephrine
3/10
In the final of insulin synthesis,the pancreatic β-cell cleaves away a portion of the proinsulin polypeptide chain,forming insulin.The removed portion is then:
- Degradedintheroughendoplasmicreticulum
- DegradedinIysosomes
- Degradedinproteasomes
- Degradedinthecytoplasm
- Packedinsecretorygranules
4/10
A 34-year-old female is being evaluated for periodic low-volume vaginal bleeding. A cytological finding on cervical smear microscopy is shown on the slide below.

Which of the following best describes the cell shown on the slide?

Which of the following best describes the cell shown on the slide?
- Endometrialcell
- Cluecell
- Parabasalcell
- Glandularcell
- Koilocyte
5/10
A 34-year-old Caucasian female presents to her primary care physician complaining of a mass in her right breast. Histological evaluation of a biopsy specimen is shown below.

What is the most likely diagnosis?

What is the most likely diagnosis?
- Ductalcarcinomainsitu(DCIS)
- Pagetdisease
- Fibroadenoma
- Sclerosingadenosis
- Mammaryductectasia
- Medullarycarcinoma
6/10
Histological evaluation of a portion of gastrointestinal.tract shows ramified, tubular glands located in submucosal layer.The glands contain secretions with pH close to 9.0 . Which of the following portions of the gastrointestinal tract is most likely inspected?
- Stomach
- Duodenum
- Jejunum
- Ileum
- Ascendingcolon
7/10
A 17-year-old man comes to the physician complaining of fever and sore throat. Physical examination reveals both cervical and axillary lymphadenopathy. A peripheral blood smear shows several white blood cells similar to the one shown in the image below.

The pathogen most likely responsible for the patient's condition is also associated with which of the following disorders?

The pathogen most likely responsible for the patient's condition is also associated with which of the following disorders?
- Analcarcinoma
- Glomerulonephritis
- Myocarditis
- Nasopharyngealcarcinoma
- Retinitis
- Tenosynovitis
8/10
A 5-year-old male is brought to clinic with a several day history of fever,irritability and refusal to eat. Physical examination demonstrates painful gingival ulcers, swollen gums, and cervical lymphadenopathy. Microscopic examination of the oral ulcer base scrapings is shown on the slide below.


- Primaryinfection
- Virusreactivation
- Latentinfection
- Abortiveinfection
- Slowvirusinfection
9/10
A 32-year-old woman comes to the physician complaining of grayish-white vaginal discharge with a 'fishy' odor. She states that she has recently become sexually active with a new partner. A cytologic specimen of the discharge is obtained and shown below. Which of the following organisms is most likely responsible for this patient's infection?


- Candidaalbicans
- Chlamydiatrachomatis
- Gardnerellavaginalis
- Herpessimplexvirus
- Humanpapillomavirus
10/10
Two proteins, kinesin and dynein, are isolated from samples of neural tissue from experimental animals.These proteins are functionally associated with which of the following cell structures?
- Nisslsubstance
- Microtubules
- Lysosomes
- Membranelipids
- Nuclearmembrane
- Intermediatefilaments
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